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Human (GRCh38.p14)
Description

DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989]

Gene Synonyms

TOP2, TOP2ALPHA, TOPIIA

Location
About this transcript

This transcript has 35 exons, is annotated with 88 domains and features, is associated with 13272 variant alleles and maps to 1212 oligo probes.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000423485.6TOP2A-20156951531aaENSP00000411532.1
 
Protein coding
CCDS45672P11388-1 NM_001067.4MANE SelectEnsembl CanonicalGENCODE PrimaryGENCODE BasicAPPRIS P1TSL:1
ENST00000581055.1TOP2A-205579147aaENSP00000462908.1
 
Protein coding
J3KTB7 -TSL:4CDS 3' incomplete
ENST00000577541.1TOP2A-20242027aaENSP00000464055.1
 
Protein coding
J3QR57 -TSL:2CDS 5' incomplete
ENST00000578412.1TOP2A-204882No protein-
 
Retained intron
--TSL:2
ENST00000577706.1TOP2A-203554No protein-
 
Retained intron
--TSL:2
Statistics

Exons: 35, Coding exons: 35, Transcript length: 5,695 bps, Translation length: 1,531 residues

MANE

This MANE Select transcript contains ENSP00000411532 and matches to NM_001067.4 and NP_001058.2

Uniprot

This transcript corresponds to the following Uniprot identifiers: P11388

CCDS

This transcript is a member of the Human CCDS set: CCDS45672

Transcript Support Level (TSL)

TSL:1

Version

ENST00000423485.6

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

GENCODE primary gene

This transcript is a member of the Gencode Primary gene set.