Human (GRCh38.p14)
Description

methylenetetrahydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:7436]

Location
About this transcript

This transcript has 12 exons, is annotated with 14 domains and features, is associated with 10491 variant alleles and maps to 918 oligo probes.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000376590.9MTHFR-2047018656aaENSP00000365775.3
 
Protein coding
CCDS137P42898-1 NM_005957.5MANE SelectEnsembl CanonicalGENCODE basicAPPRIS ALT1TSL:1
ENST00000376592.6MTHFR-2058378656aaENSP00000365777.1
 
Protein coding
CCDS137P42898-1 -GENCODE basicAPPRIS ALT1TSL:1
ENST00000376585.6MTHFR-2038094697aaENSP00000365770.1
 
Protein coding
CCDS81262P42898-2 -GENCODE basicAPPRIS ALT1TSL:5
ENST00000376583.7MTHFR-2027044697aaENSP00000365767.3
 
Protein coding
CCDS81262P42898-2 -GENCODE basicAPPRIS ALT1TSL:5
ENST00000423400.7MTHFR-2082715696aaENSP00000398908.3
 
Protein coding
CCDS90864Q5SNW7 -GENCODE basicAPPRIS P4TSL:1
ENST00000641407.1MTHFR-2102387642aaENSP00000493098.1
 
Protein coding
A0A286YFD0 -GENCODE basic
ENST00000641820.1MTHFR-2171569411aaENSP00000492937.1
 
Protein coding
L7P8G6 -GENCODE basic
ENST00000418034.1MTHFR-2071034143aaENSP00000405082.1
 
Protein coding
Q5SNW5 -TSL:3CDS 3' incomplete
ENST00000376486.3MTHFR-201875229aaENSP00000365669.3
 
Protein coding
F8W9T8 -TSL:1CDS 3' incomplete
ENST00000413656.5MTHFR-20639829aaENSP00000408307.1
 
Protein coding
A0A1B0GXD9 -TSL:1CDS 3' incomplete
ENST00000641747.1MTHFR-214322782aaENSP00000493116.1
 
Nonsense mediated decay
A0A286YF47 --
ENST00000641446.1MTHFR-2122820549aaENSP00000493262.1
 
Nonsense mediated decay
A0A286YF17 --
ENST00000431243.6MTHFR-2091116No protein-
 
Protein coding CDS not defined
--TSL:1
ENST00000641721.1MTHFR-213891No protein-
 
Protein coding CDS not defined
---
ENST00000642002.1MTHFR-219549No protein-
 
Protein coding CDS not defined
---
ENST00000641805.1MTHFR-2162945No protein-
 
Retained intron
---
ENST00000641759.1MTHFR-2152454No protein-
 
Retained intron
---
ENST00000641909.1MTHFR-2182254No protein-
 
Retained intron
---
ENST00000641437.1MTHFR-2111911No protein-
 
Retained intron
---
Statistics

Exons: 12, Coding exons: 11, Transcript length: 8,378 bps, Translation length: 656 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P42898

CCDS

This transcript is a member of the Human CCDS set: CCDS137

Transcript Support Level (TSL)

TSL:1

Version

ENST00000376592.6

Type

Protein coding

Annotation Method

Manual annotation (determined on a case-by-case basis) from the Havana project.

Annotation Attributes

upstream ATG [Definitions]

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.