Transcript: ENST00000375856.5 IRS2-201

Description

insulin receptor substrate 2 [Source:HGNC Symbol;Acc:HGNC:6126]

Location

Chromosome 13: 109,752,695-109,786,583 reverse strand.

About this transcript

This transcript has 2 exons, is annotated with 68 domains and features, is associated with 18678 variant alleles and maps to 466 oligo probes.

Gene

This transcript is a product of gene ENSG00000185950.9 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq Match	Flags
ENST00000375856.5	IRS2-201	8156	1338aa	ENSP00000365016.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS9510	Q9Y4H2	NM_003749.3	The Matched Annotation from NCBI and EMBL-EBI is a collaboration between Ensembl/GENCODE and RefSeq. The MANE Select is a default transcript per human gene that is representative of biology, well-supported, expressed and highly-conserved. This transcript set matches GRCh38 and is 100% identical between RefSeq and Ensembl/GENCODE for 5' UTR, CDS, splicing and 3'UTR.MANE Select, A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE Primary, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,

Summary

Statistics

Exons: 2, Coding exons: 2, Transcript length: 8,156 bps, Translation length: 1,338 residues

MANE

This MANE Select transcript contains ENSP00000365016 and matches to NM_003749.3 and NP_003740.2

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q9Y4H2

CCDS

This transcript is a member of the Human CCDS set: CCDS9510

Transcript Support Level (TSL)

TSL:1

Version

ENST00000375856.5

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

GENCODE primary gene

This transcript is a member of the Gencode Primary gene set.

Transcript: ENST00000375856.5 IRS2-201

Summary

About Us

Get help

Our sister sites

Follow us

Favourite species

All species

Recent locations

Transcript: ENST00000375856.5 IRS2-201

Summary

About Us

Get help

Our sister sites

Follow us