Transcript: ENST00000368507.8 ROS1-201

Description

ROS proto-oncogene 1, receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:10261]

Gene Synonyms

C-ROS-1, MCF3, ROS

Location

Chromosome 6: 117,287,353-117,425,942 reverse strand.

About this transcript

This transcript has 44 exons, is annotated with 67 domains and features, is associated with 85561 variant alleles and maps to 1078 oligo probes.

Gene

This transcript is a product of gene ENSG00000047936.11 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq Match	Flags
ENST00000368507.8	ROS1-201	8451	2341aa	ENSP00000357493.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS93994	Q5H8Y1	NM_001378902.1	The Matched Annotation from NCBI and EMBL-EBI is a collaboration between Ensembl/GENCODE and RefSeq. The MANE Select is a default transcript per human gene that is representative of biology, well-supported, expressed and highly-conserved. This transcript set matches GRCh38 and is 100% identical between RefSeq and Ensembl/GENCODE for 5' UTR, CDS, splicing and 3'UTR.MANE Select, A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 5: A transcript where no single transcript supports the model structure. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:5,
ENST00000368508.7	ROS1-202	7435	2347aa	ENSP00000357494.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS5116	P08922	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENST00000403284.2	ROS1-203	681	97aa	ENSP00000384647.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H0Y3T9	-	TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:2, 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,

Summary

Statistics

Exons: 44, Coding exons: 44, Transcript length: 8,451 bps, Translation length: 2,341 residues

MANE

This MANE Select transcript contains ENSP00000357493 and matches to NM_001378902.1 and NP_001365831.1

CCDS

This transcript is a member of the Human CCDS set: CCDS93994

Transcript Support Level (TSL)

TSL:5

Version

ENST00000368507.8

Type

Protein coding

Annotation Method

Manual annotation (determined on a case-by-case basis) from the Havana project.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript: ENST00000368507.8 ROS1-201

Summary

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Transcript: ENST00000368507.8 ROS1-201

Summary

About Us

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