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Human (GRCh38.p14)
Description

mitogen-activated protein kinase kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6855]

Gene Synonyms

MAPKKK3, MEKK3

Location
About this transcript

This transcript has 16 exons, is annotated with 25 domains and features, is associated with 29936 variant alleles and maps to 668 oligo probes.

Gene
Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000361733.8MAP3K3-2024752626aaENSP00000354485.4
 
Protein coding
CCDS32702Q99759-1 NM_002401.5MANE SelectEnsembl CanonicalGENCODE PrimaryGENCODE BasicAPPRIS ALT1TSL:1
ENST00000361357.7MAP3K3-2014818657aaENSP00000354927.3
 
Protein coding
CCDS32701Q99759-2 -GENCODE BasicAPPRIS P4TSL:1
ENST00000579585.5MAP3K3-2083352657aaENSP00000461988.1
 
Protein coding
CCDS32701Q99759-2 -GENCODE PrimaryGENCODE BasicAPPRIS P4TSL:1
ENST00000584573.5MAP3K3-2102480653aaENSP00000464130.1
 
Protein coding
CCDS86624J3QRB6 -GENCODE PrimaryGENCODE BasicAPPRIS ALT1TSL:1
ENST00000577395.5MAP3K3-2032016622aaENSP00000462086.1
 
Protein coding
CCDS82186J3KRN4 -GENCODE BasicAPPRIS ALT1TSL:1
ENST00000577597.5MAP3K3-204202456aaENSP00000462917.1
 
Nonsense mediated decay
J3KTC4 -TSL:1
ENST00000585302.1MAP3K3-21167831aaENSP00000464532.1
 
Nonsense mediated decay
J3QS54 -TSL:3CDS 5' incomplete
ENST00000581732.1MAP3K3-20958042aaENSP00000464482.1
 
Nonsense mediated decay
J3QS19 -TSL:4CDS 5' incomplete
ENST00000577784.1MAP3K3-205565No protein-
 
Protein coding CDS not defined
--TSL:4
ENST00000577839.1MAP3K3-206594No protein-
 
Retained intron
--TSL:3
ENST00000578622.5MAP3K3-207560No protein-
 
Retained intron
--TSL:4
Statistics

Exons: 16, Coding exons: 16, Transcript length: 4,752 bps, Translation length: 626 residues

MANE

This MANE Select transcript contains ENSP00000354485 and matches to NM_002401.5 and NP_002392.2

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q99759

CCDS

This transcript is a member of the Human CCDS set: CCDS32702

Transcript Support Level (TSL)

TSL:1

Version

ENST00000361733.8

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

GENCODE primary gene

This transcript is a member of the Gencode Primary gene set.