Upcoming Ensembl Platform Transition

This is the final release of its kind on this website.

In summer 2026, this site will bring you to the new Ensembl platform currently at beta.ensembl.org.
Please bookmark this archive to retain access to the current site, tools and functionality until they are available on the new platform -> jun2026.archive.ensembl.org

Human (GRCh38.p14)
Description

C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025]

Gene Synonyms

3-10C, AMCF-I, B-ENAP, GCP-1, GCP1, IL-8, IL8, K60, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1, SCYB8, TSG-1

Location
About this transcript

This transcript has 4 exons, is annotated with 56 domains and features, is associated with 1552 variant alleles and maps to 359 oligo probes.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000307407.8CXCL8-201164299aaENSP00000306512.3
 
Protein coding
CCDS34005P10145 NM_000584.4MANE SelectEnsembl CanonicalGENCODE PrimaryGENCODE BasicAPPRIS P1TSL:1
ENST00001138632.1CXCL8-206167099aaENSP00000805838.1
 
Protein coding
CCDS34005--Ensembl Canonical ExtendedGENCODE BasicAPPRIS P1
ENST00000401931.2CXCL8-202574995aaENSP00000385908.1
 
Protein coding
CCDS87231C9J4T6 -GENCODE PrimaryGENCODE BasicTSL:1
ENST00000696131.1CXCL8-204201840aaENSP00000512424.1
 
Nonsense mediated decay
A0A8Q3SIG6 --
ENST00000696132.1CXCL8-205174240aaENSP00000512425.1
 
Nonsense mediated decay
A0A8Q3SIG6 --
ENST00000483500.1CXCL8-203599No protein-
 
Retained intron
--TSL:2
Statistics

Exons: 4, Coding exons: 4, Transcript length: 1,642 bps, Translation length: 99 residues

MANE

This MANE Select transcript contains ENSP00000306512 and matches to NM_000584.4 and NP_000575.1

Uniprot

This transcript corresponds to the following Uniprot identifiers: P10145

CCDS

This transcript is a member of the Human CCDS set: CCDS34005

Transcript Support Level (TSL)

TSL:1

Version

ENST00000307407.8

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

GENCODE primary gene

This transcript is a member of the Gencode Primary gene set.