Transcript: ENST00000261667.8 KPNA3-201

Description

karyopherin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6396]

Gene Synonyms

HSRP1, IPOA4, SRP1GAMMA, SRP4

Location

Chromosome 13: 49,699,320-49,792,682 reverse strand.

About this transcript

This transcript has 17 exons, is annotated with 30 domains and features, is associated with 41467 variant alleles and maps to 714 oligo probes.

Gene

This transcript is a product of gene ENSG00000102753.10 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq Match	Flags
ENST00000261667.8	KPNA3-201	4222	521aa	ENSP00000261667.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS9421	O00505	NM_002267.4	The Matched Annotation from NCBI and EMBL-EBI is a collaboration between Ensembl/GENCODE and RefSeq. The MANE Select is a default transcript per human gene that is representative of biology, well-supported, expressed and highly-conserved. This transcript set matches GRCh38 and is 100% identical between RefSeq and Ensembl/GENCODE for 5' UTR, CDS, splicing and 3'UTR.MANE Select, A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE Primary, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENST00000436760.1	KPNA3-202	588	91aa	ENSP00000393869.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		H0Y4S9	-	TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:2, 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,

Summary

Statistics

Exons: 17, Coding exons: 17, Transcript length: 4,222 bps, Translation length: 521 residues

MANE

This MANE Select transcript contains ENSP00000261667 and matches to NM_002267.4 and NP_002258.2

Uniprot

This transcript corresponds to the following Uniprot identifiers: O00505

CCDS

This transcript is a member of the Human CCDS set: CCDS9421

Transcript Support Level (TSL)

TSL:1

Version

ENST00000261667.8

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

GENCODE primary gene

This transcript is a member of the Gencode Primary gene set.

Transcript: ENST00000261667.8 KPNA3-201

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Transcript: ENST00000261667.8 KPNA3-201

Summary

About Us

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