Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
- Variant table
- Variant image
- Structural variants
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: Top2a ENSRNOG00000053047

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Description

DNA topoisomerase II alpha [Source:RGD Symbol;Acc:62048]

Location

Primary_assembly 10: 83,945,735-83,976,874 reverse strand.

mRatBN7.2:CM026983.1

About this gene

This gene has 3 transcripts (splice variants), 209 orthologues, 1 paralogue and is associated with 26 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSRNOT00000085344.2	Top2a-202	5553	1528aa	ENSRNOP00000069963.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A0G2JWP8	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1,
ENSRNOT00000096403.1	Top2a-203	5580	1524aa	ENSRNOP00000091216.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8I6ADA9	-
ENSRNOT00000081440.2	Top2a-201	5189	1500aa	ENSRNOP00000069083.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A0G2JUF8	-

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Summary

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