Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Biological process
- GO: Cellular component
- GO: Molecular function
Phenotypes
Genetic Variation
- Variant table
- Variant image
- Structural variants
Gene expression
Pathway
Molecular interactions
External references
Supporting evidence
ID History
- Gene history

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Gene: Insr ENSRNOG00000029986

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Description

insulin receptor [Source:RGD Symbol;Acc:2917]

Gene Synonyms

IR

Location

Primary_assembly 12: 5,981,835-6,128,803 reverse strand.

GRCr8:CM070402.1

About this gene

This gene has 3 transcripts (splice variants), 289 orthologues, 53 paralogues and is associated with 55 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSRNOT00000067448.5	Insr-202	5399	1384aa	ENSRNOP00000060141.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A9K3Y780 T2CB11	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSRNOT00000113217.2	Insr-203	5429	1359aa	ENSRNOP00000079583.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8I5ZMZ8	APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,
ENSRNOT00000041155.5	Insr-201	5399	1384aa	ENSRNOP00000049655.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8J8Y5N6	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,

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Summary

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