Gene: Mpl ENSRNOG00000028377

Description

MPL proto-oncogene, thrombopoietin receptor [Source:RGD Symbol;Acc:1311069]

Gene Synonyms

LOC366455

Location

mRatBN7.2:CM026978.1

About this gene

This gene has 2 transcripts (splice variants), 186 orthologues, 7 paralogues and is associated with 20 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSRNOT00000093301.2	Mpl-201	3046	644aa	ENSRNOP00000076315.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A1W2Q6N1	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,
ENSRNOT00000093708.2	Mpl-202	1434	460aa	ENSRNOP00000076155.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A1W2Q670	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,

Summary