Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Anatomical entity
Phenotypes
Genetic Variation
- Variant table
- Variant image
- Structural variants
Gene expression
Pathway
Molecular interactions
External references
Supporting evidence
ID History
- Gene history

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Gene: Spast ENSRNOG00000027136

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Description

spastin [Source:RGD Symbol;Acc:1308494]

Gene Synonyms

LOC362700, Spg4

Location

Primary_assembly 6: 26,807,220-26,858,446 reverse strand.

GRCr8:CM070396.1

About this gene

This gene has 5 transcripts (splice variants), 235 orthologues, 9 paralogues and is associated with 16 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSRNOT00000079137.3	Spast-202	4852	613aa	ENSRNOP00000073338.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A0G2K590	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,
ENSRNOT00000105595.2	Spast-203	4756	581aa	ENSRNOP00000085299.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8I6A3R4 B2RYN7	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSRNOT00000159739.1	Spast-204	4711	590aa	ENSRNOP00000099795.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	-	-
ENSRNOT00000039375.7	Spast-201	4705	564aa	ENSRNOP00000033763.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8L2QK18	-
ENSRNOT00000173450.1	Spast-205	4609	532aa	ENSRNOP00000110215.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	-	-

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Summary

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