Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Biological process
- GO: Cellular component
- GO: Molecular function
Phenotypes
Genetic Variation
- Variant table
- Variant image
- Structural variants
Gene expression
Pathway
Molecular interactions
External references
Supporting evidence
ID History
- Gene history

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Gene: Lmna ENSRNOG00000019638

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Description

lamin A/C [Source:RGD Symbol;Acc:620456]

Location

Primary_assembly 2: 176,237,564-176,288,072 reverse strand.

GRCr8:CM070392.1

About this gene

This gene has 5 transcripts (splice variants), 261 orthologues, 72 paralogues and is associated with 85 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSRNOT00000082174.3	Lmna-202	3581	879aa	ENSRNOP00000068655.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A0G2JTC5	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,
ENSRNOT00000084455.3	Lmna-203	3657	848aa	ENSRNOP00000072742.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A0G2K3R2	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSRNOT00000026705.8	Lmna-201	3519	802aa	ENSRNOP00000026705.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	G3V8L3	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSRNOT00000092993.3	Lmna-204	1759	462aa	ENSRNOP00000076028.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A1B0GWU9 A6J682	-
ENSRNOT00000156941.1	Lmna-205	1572	442aa	ENSRNOP00000110164.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	-	-

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Summary

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