Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Anatomical entity
Phenotypes
Genetic Variation
- Variant table
- Variant image
- Structural variants
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: Apoe ENSRNOG00000018454

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Description

apolipoprotein E [Source:RGD Symbol;Acc:2138]

Gene Synonyms

apo-E

Location

Primary_assembly 1: 88,481,385-88,485,855 reverse strand.

GRCr8:CM070391.1

About this gene

This gene has 4 transcripts (splice variants), 221 orthologues, 3 paralogues and is associated with 149 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSRNOT00000080453.3	Apoe-202	1189	359aa	ENSRNOP00000071702.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A0G2K151	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSRNOT00000108411.2	Apoe-204	1668	305aa	ENSRNOP00000092257.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8I6ADM8	APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,
ENSRNOT00000091574.3	Apoe-203	1174	353aa	ENSRNOP00000068937.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8L2R071	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSRNOT00000041891.7	Apoe-201	1114	333aa	ENSRNOP00000050968.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8L2QPE1	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,

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Summary

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