Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Biological process
- GO: Molecular function
- GO: Cellular component
Phenotypes
Genetic Variation
- Variant table
- Variant image
- Structural variants
Gene expression
Pathway
Molecular interactions
External references
Supporting evidence
ID History
- Gene history

Configure this page

Share this page

Bookmark this page

.

Gene: Optn ENSRNOG00000017941

.

Description

optineurin [Source:RGD Symbol;Acc:628886]

Gene Synonyms

Fip2

Location

Primary_assembly 17: 78,118,866-78,169,543 forward strand.

GRCr8:CM070407.1

About this gene

This gene has 3 transcripts (splice variants), 208 orthologues, 1 paralogue and is associated with 27 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSRNOT00000042881.8	Optn-201	4234	647aa	ENSRNOP00000045795.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	F1M9C4	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,
ENSRNOT00000074087.4	Optn-202	4077	585aa	ENSRNOP00000066459.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	M0RAB4	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSRNOT00000091561.3	Optn-203	4029	569aa	ENSRNOP00000072832.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A0G2K3Z1	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,

.

Summary

.

.