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Gene: Hmgcr ENSRNOG00000016122

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Description

3-hydroxy-3-methylglutaryl-CoA reductase [Source:RGD Symbol;Acc:2803]

Gene Synonyms

3H3M

Location

Primary_assembly 2: 29,720,553-29,754,533 reverse strand.

GRCr8:CM070392.1

About this gene

This gene has 6 transcripts (splice variants), 269 orthologues and is associated with 44 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSRNOT00000112347.2	Hmgcr-204	4484	897aa	ENSRNOP00000087297.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8I6A6Z9	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSRNOT00000096437.2	Hmgcr-202	4629	896aa	ENSRNOP00000097467.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8I6AV02	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSRNOT00000101787.2	Hmgcr-203	4305	887aa	ENSRNOP00000096084.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8I6AUL2 A6I512 P51639	APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,
ENSRNOT00000022055.6	Hmgcr-201	4278	878aa	ENSRNOP00000022055.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8L2QCN8	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSRNOT00000128811.1	Hmgcr-205	3694	880aa	ENSRNOP00000106905.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	-	-
ENSRNOT00000165922.1	Hmgcr-206	3667	871aa	ENSRNOP00000108611.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	-	-

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Summary

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