Gene: Lrrk1 ENSRNOG00000012730

Description

leucine-rich repeat kinase 1 [Source:RGD Symbol;Acc:1308000]

Gene Synonyms

LOC308703

Location

GRCr8:CM070391.1

About this gene

This gene has 2 transcripts (splice variants), 179 orthologues, 31 paralogues and is associated with 4 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSRNOT00000016959.8	Lrrk1-201	7468	2094aa	ENSRNOP00000016959.7	Gene/transcipt that contains an open reading frame (ORF).Protein coding	D3ZRJ7	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSRNOT00000106564.2	Lrrk1-202	6517	1996aa	ENSRNOP00000094655.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8I6B1B9	APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,

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