Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Biological process
- GO: Cellular component
- GO: Molecular function
Phenotypes
Genetic Variation
- Variant table
- Variant image
- Structural variants
Gene expression
Pathway
Molecular interactions
External references
Supporting evidence
ID History
- Gene history

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Gene: Casp8 ENSRNOG00000012331

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Description

caspase 8 [Source:RGD Symbol;Acc:620945]

Gene Synonyms

CASP-8

Location

Primary_assembly 9: 67,758,033-67,806,699 forward strand.

GRCr8:CM070399.1

About this gene

This gene has 2 transcripts (splice variants), 132 orthologues, 11 paralogues and is associated with 76 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSRNOT00000016613.6	Casp8-201	2345	504aa	ENSRNOP00000016613.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	Q9JHX4	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSRNOT00000140357.1	Casp8-202	2426	482aa	ENSRNOP00000103046.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	-	APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,

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Summary

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