Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Molecular function
- GO: Cellular component
- GO: Biological process
Phenotypes
Genetic Variation
- Variant table
- Variant image
- Structural variants
Gene expression
Pathway
Molecular interactions
External references
Supporting evidence
ID History
- Gene history

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Gene: Comt ENSRNOG00000001889

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Description

catechol-O-methyltransferase [Source:RGD Symbol;Acc:2379]

Location

Primary_assembly 11: 96,072,489-96,092,533 forward strand.

GRCr8:CM070401.1

About this gene

This gene has 3 transcripts (splice variants), 274 orthologues, 2 paralogues and is associated with 77 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSRNOT00000104392.2	Comt-202	2180	306aa	ENSRNOP00000092582.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8I6AHB1	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,
ENSRNOT00000050269.7	Comt-201	1653	264aa	ENSRNOP00000043148.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	P22734-2	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSRNOT00000119057.2	Comt-203	1606	265aa	ENSRNOP00000086073.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8I6A1I0	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,

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Summary

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