Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
- Genomic alignments
- Gene tree
- Gene gain/loss tree
- Orthologues
- Paralogues
- Strains
  - Gene tree
  - Orthologues
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Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
External references
Supporting evidence
ID History
- Gene history

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Gene: Thbd ENSMUSG00000074743

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Description

thrombomodulin [Source:MGI Symbol;Acc:MGI:98736]

Gene Synonyms

CD141, TM

Location

Chromosome 2: 148,216,045-148,250,201 reverse strand.

GRCm39:CM000995.3

About this gene

This gene has 4 transcripts (splice variants), 67 orthologues and is associated with 39 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000099270.5	Thbd-201	3723	577aa	ENSMUSP00000096877.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS16838	P15306 Q543W3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE Primary, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL NA: A transcript that was not analysed for TSL. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:NA,
ENSMUST00000502005.1	Thbd-202	5122	577aa	ENSMUSP00000280368.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS16838	Q543W3	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1,
ENSMUST00000502006.1	Thbd-203	4794	577aa	ENSMUSP00000280369.1	Nonsense mediated decay	CCDS16838	Q543W3	-
ENSMUST00000502007.1	Thbd-204	2694	577aa	ENSMUSP00000280370.1	Nonsense mediated decay	CCDS16838	Q543W3	-

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Summary

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