Gene: Mars1 ENSMUSG00000040354

Description

methionine-tRNA synthetase 1 [Source:MGI Symbol;Acc:MGI:1345633]

Gene Synonyms

Mars, MetRS, methionine tRNA ligase, methionyl-tRNA synthetase

Location

Chromosome 10: 127,128,344-127,147,776 reverse strand.

GRCm39:CM001003.3

About this gene

This gene has 40 transcripts (splice variants), 199 orthologues, 7 paralogues and is associated with 4 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000037290.12	Mars1-201	2939	902aa	ENSMUSP00000037446.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS24237	Q68FL6	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE Primary, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P4: Where the APPRIS core modules are unable to choose a clear principal CDS and there is more than one variant with a distinct (but consecutive) CCDS identifiers, APPRIS selects the longest CCDS isoform as the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P4, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000171564.9	Mars1-206	2963	910aa	ENSMUSP00000130666.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS48716	E9QB02	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS ALT1: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that is conserved in at least three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT1, TSL 5: A transcript where no single transcript supports the model structure. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:5,
ENSMUST00000473676.1	Mars1-226	2955	852aa	ENSMUSP00000252039.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENSMUST00000473674.1	Mars1-224	2929	844aa	ENSMUSP00000252037.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENSMUST00000547103.1	Mars1-239	2822	863aa	ENSMUSP00000325466.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENSMUST00000473672.1	Mars1-222	2735	834aa	ENSMUSP00000252035.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENSMUST00000134778.3	Mars1-203	621	184aa	ENSMUSP00000118031.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding		F6W0G8	TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3, 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENSMUST00000473657.1	Mars1-207	6634	828aa	ENSMUSP00000252020.1	Nonsense mediated decay		-	-
ENSMUST00000473658.1	Mars1-208	6542	110aa	ENSMUSP00000252021.1	Nonsense mediated decay		-	-
ENSMUST00000473660.1	Mars1-210	5148	278aa	ENSMUSP00000252023.1	Nonsense mediated decay		-	-
ENSMUST00000473659.1	Mars1-209	5042	45aa	ENSMUSP00000252022.1	Nonsense mediated decay		-	-
ENSMUST00000473661.1	Mars1-211	4779	741aa	ENSMUSP00000252024.1	Nonsense mediated decay		-	-
ENSMUST00000473662.1	Mars1-212	4772	597aa	ENSMUSP00000252025.1	Nonsense mediated decay		-	-
ENSMUST00000473663.1	Mars1-213	4459	597aa	ENSMUSP00000252026.1	Nonsense mediated decay		-	-
ENSMUST00000547099.1	Mars1-235	4449	741aa	ENSMUSP00000325462.1	Nonsense mediated decay		-	-
ENSMUST00000547100.1	Mars1-236	4401	201aa	ENSMUSP00000325463.1	Nonsense mediated decay		-	-
ENSMUST00000473664.1	Mars1-214	3444	835aa	ENSMUSP00000252027.1	Nonsense mediated decay		-	-
ENSMUST00000473667.1	Mars1-217	3333	278aa	ENSMUSP00000252030.1	Nonsense mediated decay		-	-
ENSMUST00000473669.1	Mars1-219	3081	101aa	ENSMUSP00000252032.1	Nonsense mediated decay		-	-
ENSMUST00000473678.1	Mars1-228	3046	292aa	ENSMUSP00000252041.1	Nonsense mediated decay		-	-
ENSMUST00000473675.1	Mars1-225	3028	201aa	ENSMUSP00000252038.1	Nonsense mediated decay		-	-
ENSMUST00000547104.1	Mars1-240	2956	257aa	ENSMUSP00000325467.1	Nonsense mediated decay		-	-
ENSMUST00000547101.1	Mars1-237	2944	101aa	ENSMUSP00000325464.1	Nonsense mediated decay		-	-
ENSMUST00000473681.1	Mars1-231	2932	257aa	ENSMUSP00000252044.1	Nonsense mediated decay		-	-
ENSMUST00000473668.1	Mars1-218	2914	741aa	ENSMUSP00000252031.1	Nonsense mediated decay		-	-
ENSMUST00000473666.1	Mars1-216	2911	292aa	ENSMUSP00000252029.1	Nonsense mediated decay		-	-
ENSMUST00000473682.1	Mars1-232	2906	741aa	ENSMUSP00000252045.1	Nonsense mediated decay		-	-
ENSMUST00000473671.1	Mars1-221	2871	378aa	ENSMUSP00000252034.1	Nonsense mediated decay		-	-
ENSMUST00000547102.1	Mars1-238	2868	663aa	ENSMUSP00000325465.1	Nonsense mediated decay		-	-
ENSMUST00000473665.1	Mars1-215	2844	72aa	ENSMUSP00000252028.1	Nonsense mediated decay		-	-
ENSMUST00000473670.1	Mars1-220	2835	250aa	ENSMUSP00000252033.1	Nonsense mediated decay		-	-
ENSMUST00000473677.1	Mars1-227	2817	737aa	ENSMUSP00000252040.1	Nonsense mediated decay		-	-
ENSMUST00000473680.1	Mars1-230	2808	810aa	ENSMUSP00000252043.1	Nonsense mediated decay		-	-
ENSMUST00000473679.1	Mars1-229	2805	590aa	ENSMUSP00000252042.1	Nonsense mediated decay		-	-
ENSMUST00000473684.1	Mars1-234	2798	212aa	ENSMUSP00000252047.1	Nonsense mediated decay		-	-
ENSMUST00000473673.1	Mars1-223	2722	257aa	ENSMUSP00000252036.1	Nonsense mediated decay		-	-
ENSMUST00000473683.1	Mars1-233	2598	378aa	ENSMUSP00000252046.1	Nonsense mediated decay		-	-
ENSMUST00000145275.8	Mars1-205	3065	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:2,
ENSMUST00000128369.2	Mars1-202	574	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3,
ENSMUST00000139683.2	Mars1-204	467	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,

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Gene: Mars1 ENSMUSG00000040354

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Gene: Mars1 ENSMUSG00000040354

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