Gene: Dis3 ENSMUSG00000033166

Description

DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease [Source:MGI Symbol;Acc:MGI:1919912]

Gene Synonyms

2810028N01Rik

Location

Chromosome 14: 99,312,642-99,337,206 reverse strand.

GRCm39:CM001007.3

About this gene

This gene has 6 transcripts (splice variants), 239 orthologues, 2 paralogues and is associated with 11 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000042471.11	Dis3-201	5150	958aa	ENSMUSP00000041906.10	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS49555	Q9CSH3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE Primary, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 5: A transcript where no single transcript supports the model structure. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:5,
ENSMUST00000227022.2	Dis3-203	3590	116aa	ENSMUSP00000154489.2	Nonsense mediated decay		A0A2I3BR88	-
ENSMUST00000228643.2	Dis3-205	2971	566aa	ENSMUSP00000154479.2	Nonsense mediated decay		A0A2I3BR78	-
ENSMUST00000227001.2	Dis3-202	356	No protein	-	Alternatively spliced transcript of a protein coding gene for which we cannot define a CDS.Protein coding CDS not defined		-	-
ENSMUST00000228449.2	Dis3-204	3726	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-
ENSMUST00000228756.2	Dis3-206	672	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-

Gene: Dis3 ENSMUSG00000033166

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Gene: Dis3 ENSMUSG00000033166

Summary

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