Gene: Il6ra ENSMUSG00000027947

Description

interleukin 6 receptor, alpha [Source:MGI Symbol;Acc:MGI:105304]

Gene Synonyms

CD126, IL-6 receptor alpha chain, IL-6R, Il6r

Location

Chromosome 3: 89,771,366-89,820,719 reverse strand.

GRCm39:CM000996.3

About this gene

This gene has 4 transcripts (splice variants), 526 orthologues, 24 paralogues and is associated with 19 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000197679.5	Il6ra-202	8639	459aa	ENSMUSP00000143541.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS79954	A0A0G2JGF1	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE Primary, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000029559.8	Il6ra-201	8642	460aa	ENSMUSP00000029559.7	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS38496	P22272	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000525842.1	Il6ra-203	2751	316aa	ENSMUSP00000304205.1	Nonsense mediated decay		-	-
ENSMUST00000525843.1	Il6ra-204	2557	236aa	ENSMUSP00000304206.1	Nonsense mediated decay		-	-

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Gene: Il6ra ENSMUSG00000027947

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Gene: Il6ra ENSMUSG00000027947

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