Gene: Dhfr ENSMUSG00000021707

Description

dihydrofolate reductase [Source:MGI Symbol;Acc:MGI:94890]

Gene Synonyms

8430436I03Rik

Location

Chromosome 13: 92,491,194-92,525,641 forward strand.

GRCm39:CM001006.3

About this gene

This gene has 7 transcripts (splice variants), 357 orthologues, 1 paralogue and is associated with 29 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000022218.7	Dhfr-201	5427	187aa	ENSMUSP00000022218.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS26680	P00375 Q544T5	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE Primary, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000510663.1	Dhfr-202	5311	129aa	ENSMUSP00000289026.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENSMUST00000510666.1	Dhfr-205	5184	106aa	ENSMUSP00000289029.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENSMUST00000565398.1	Dhfr-207	5078	83aa	ENSMUSP00000343761.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENSMUST00000510664.1	Dhfr-203	2782	168aa	ENSMUSP00000289027.1	Nonsense mediated decay		-	-
ENSMUST00000510665.1	Dhfr-204	2544	62aa	ENSMUSP00000289028.1	Nonsense mediated decay		-	-
ENSMUST00000565397.1	Dhfr-206	1617	124aa	ENSMUSP00000343760.1	Nonsense mediated decay		-	-

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Gene: Dhfr ENSMUSG00000021707

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Gene: Dhfr ENSMUSG00000021707

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