Gene: Arhgef28 ENSMUSG00000021662

Description

Rho guanine nucleotide exchange factor 28 [Source:MGI Symbol;Acc:MGI:1346016]

Gene Synonyms

9230110L08Rik, D13Bwg1089e, RIP2, Rgnef, Rho specific exchange factor, RhoGEF, p190RhoGEF

Location

Chromosome 13: 98,035,977-98,342,947 reverse strand.

GRCm39:CM001006.3

About this gene

This gene has 7 transcripts (splice variants), 276 orthologues, 8 paralogues and is associated with 6 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000109426.3	Arhgef28-201	5387	1700aa	ENSMUSP00000105053.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS36758	P97433-1	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE Primary, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000238746.2	Arhgef28-207	4660	1387aa	ENSMUSP00000158740.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A0A571BEH9	APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,
ENSMUST00000223849.2	Arhgef28-202	2001	643aa	ENSMUSP00000153000.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A0A286YCY0	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENSMUST00000224866.2	Arhgef28-203	203	11aa	ENSMUSP00000153114.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A0A286YD71	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENSMUST00000225884.2	Arhgef28-206	5307	1324aa	ENSMUSP00000153423.2	Nonsense mediated decay		P97433-2	-
ENSMUST00000225663.2	Arhgef28-205	4977	No protein	-	Alternatively spliced transcript of a protein coding gene for which we cannot define a CDS.Protein coding CDS not defined		-	-
ENSMUST00000225269.2	Arhgef28-204	783	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-

Gene: Arhgef28 ENSMUSG00000021662

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Gene: Arhgef28 ENSMUSG00000021662

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