Upcoming Ensembl Platform Transition

This is the final release of its kind on this website.

In summer 2026, this site will bring you to the new Ensembl platform currently at beta.ensembl.org.
Please bookmark this archive to retain access to the current site, tools and functionality until they are available on the new platform -> jun2026.archive.ensembl.org

Human (GRCh38.p14)
Description

prolyl endopeptidase [Source:HGNC Symbol;Acc:HGNC:9358]

Location

Chromosome 6: 105,273,218-105,454,062 reverse strand.

GRCh38:CM000668.2

About this gene

This gene has 18 transcripts (splice variants), 210 orthologues and 1 paralogue.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000652536.2PREP-2037250710aaENSP00000499089.1
 
Protein coding
CCDS5053P48147 NM_002726.5MANE SelectEnsembl CanonicalGENCODE PrimaryGENCODE BasicAPPRIS P3
ENST00001136172.1PREP-2187481710aaENSP00000815234.1
 
Protein coding
CCDS5053--Ensembl Canonical ExtendedGENCODE BasicAPPRIS P3
ENST00000369110.9PREP-2017824644aaENSP00000358106.4
 
Protein coding
A0A499FJL1 -GENCODE BasicTSL:1
ENST00000969640.2PREP-2107547732aaENSP00000639699.1
 
Protein coding
--GENCODE Basic
ENST00000910823.2PREP-2067472707aaENSP00000580882.1
 
Protein coding
--GENCODE BasicAPPRIS ALT1
ENST00000910825.2PREP-2087472707aaENSP00000580884.1
 
Protein coding
--GENCODE BasicAPPRIS ALT1
ENST00000910821.2PREP-2047430693aaENSP00000580880.1
 
Protein coding
--GENCODE Basic
ENST00001019717.1PREP-2147324567aaENSP00000689534.1
 
Protein coding
--GENCODE Basic
ENST00000910822.2PREP-2057289646aaENSP00000580881.1
 
Protein coding
--GENCODE Basic
ENST00000920421.2PREP-2097280643aaENSP00000590480.1
 
Protein coding
--GENCODE Basic
ENST00000910824.2PREP-2077238629aaENSP00000580883.1
 
Protein coding
--GENCODE Basic
ENST00000969641.2PREP-2117097582aaENSP00000639700.1
 
Protein coding
--GENCODE Basic
ENST00000448705.1PREP-20296145aaENSP00000401796.1
 
Protein coding
H0Y5Y0 -TSL:2CDS 5' incomplete
ENST00001019720.1PREP-2173034449aaENSP00000689537.1
 
Nonsense mediated decay
---
ENST00001019715.1PREP-2122894449aaENSP00000689532.1
 
Nonsense mediated decay
---
ENST00001019716.1PREP-213281282aaENSP00000689533.1
 
Nonsense mediated decay
---
ENST00001019718.1PREP-2152704519aaENSP00000689535.1
 
Nonsense mediated decay
---
ENST00001019719.1PREP-2162621495aaENSP00000689536.1
 
Nonsense mediated decay
---