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Human (GRCh38.p14)
Description

mitogen-activated protein kinase kinase kinase kinase 4 [Source:HGNC Symbol;Acc:HGNC:6866]

Gene Synonyms

FLH21957, HGK, NIK

Location

Chromosome 2: 101,696,850-101,894,690 forward strand.

GRCh38:CM000664.2

About this gene

This gene has 55 transcripts (splice variants), 281 orthologues, 35 paralogues and is associated with 1 phenotype.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000324219.9MAP4K4-20179701384aaENSP00000313644.6
 
Protein coding
CCDS92821G5E948 NM_001395002.1MANE SelectEnsembl CanonicalGENCODE PrimaryGENCODE BasicAPPRIS P3TSL:5
ENST00001142613.1MAP4K4-25583571384aaENSP00000806346.1
 
Protein coding
CCDS92821--Ensembl Canonical ExtendedGENCODE BasicAPPRIS P3
ENST00000902131.2MAP4K4-22081171304aaENSP00000572190.1
 
Protein coding
--GENCODE PrimaryGENCODE BasicAPPRIS ALT1
ENST00000971084.2MAP4K4-24181141303aaENSP00000641143.1
 
Protein coding
--GENCODE BasicAPPRIS ALT1
ENST00000350878.10MAP4K4-20380241273aaENSP00000343658.5
 
Protein coding
CCDS74546O95819-6 -GENCODE BasicTSL:1
ENST00000971083.2MAP4K4-24079791258aaENSP00000641142.1
 
Protein coding
--GENCODE PrimaryGENCODE Basic
ENST00000902137.2MAP4K4-22679761257aaENSP00000572196.1
 
Protein coding
--GENCODE Basic
ENST00000902130.2MAP4K4-21979551250aaENSP00000572189.1
 
Protein coding
--GENCODE Basic
ENST00000971089.2MAP4K4-24679521249aaENSP00000641148.1
 
Protein coding
--GENCODE Basic
ENST00000971087.2MAP4K4-24479491248aaENSP00000641146.1
 
Protein coding
--GENCODE PrimaryGENCODE Basic
ENST00000933919.2MAP4K4-23279251240aaENSP00000603978.1
 
Protein coding
--GENCODE BasicAPPRIS ALT1
ENST00000971088.2MAP4K4-24579251240aaENSP00000641147.1
 
Protein coding
--GENCODE PrimaryGENCODE Basic
ENST00000425019.7MAP4K4-20879101235aaENSP00000392830.2
 
Protein coding
CCDS92823E7EN19 -GENCODE BasicTSL:5
ENST00000933922.2MAP4K4-23579071234aaENSP00000603981.1
 
Protein coding
--GENCODE Basic
ENST00000933924.2MAP4K4-23779011232aaENSP00000603983.1
 
Protein coding
--GENCODE Basic
ENST00000933921.2MAP4K4-23478981231aaENSP00000603980.1
 
Protein coding
--GENCODE Basic
ENST00000971086.2MAP4K4-24378861227aaENSP00000641145.1
 
Protein coding
--GENCODE Basic
ENST00000971091.2MAP4K4-24878831226aaENSP00000641150.1
 
Protein coding
--GENCODE Basic
ENST00000971090.2MAP4K4-24778681221aaENSP00000641149.1
 
Protein coding
--GENCODE Basic
ENST00000971092.2MAP4K4-24978681221aaENSP00000641151.1
 
Protein coding
--GENCODE Basic
ENST00000902132.2MAP4K4-22178621219aaENSP00000572191.1
 
Protein coding
--GENCODE Basic
ENST00000902141.2MAP4K4-23078621219aaENSP00000572200.1
 
Protein coding
--GENCODE Basic
ENST00000902133.2MAP4K4-22278591218aaENSP00000572192.1
 
Protein coding
--GENCODE Basic
ENST00000625522.4MAP4K4-21678411212aaENSP00000486116.2
 
Protein coding
CCDS92822O95819-2 -GENCODE BasicTSL:5
ENST00000902136.2MAP4K4-22578321209aaENSP00000572195.1
 
Protein coding
--GENCODE Basic
ENST00000902135.2MAP4K4-22477871194aaENSP00000572194.1
 
Protein coding
--GENCODE Basic
ENST00000971095.2MAP4K4-25277841193aaENSP00000641154.1
 
Protein coding
--GENCODE Basic
ENST00000902140.2MAP4K4-22977631186aaENSP00000572199.1
 
Protein coding
--GENCODE Basic
ENST00000902139.2MAP4K4-22877601185aaENSP00000572198.1
 
Protein coding
--GENCODE Basic
ENST00000902134.2MAP4K4-22377241173aaENSP00000572193.1
 
Protein coding
--GENCODE Basic
ENST00000933925.2MAP4K4-23877031166aaENSP00000603984.1
 
Protein coding
--GENCODE Basic
ENST00000634702.2MAP4K4-21877001165aaENSP00000489579.1
 
Protein coding
CCDS82487O95819-4 -GENCODE BasicTSL:1
ENST00000971082.2MAP4K4-23976941163aaENSP00000641141.1
 
Protein coding
--GENCODE Basic
ENST00000933923.2MAP4K4-23676911162aaENSP00000603982.1
 
Protein coding
--GENCODE Basic
ENST00000933920.2MAP4K4-23376701155aaENSP00000603979.1
 
Protein coding
--GENCODE Basic
ENST00000413150.7MAP4K4-20476671154aaENSP00000389752.1
 
Protein coding
E7ENQ1 -GENCODE BasicTSL:5
ENST00000902138.2MAP4K4-22776461147aaENSP00000572197.1
 
Protein coding
--GENCODE PrimaryGENCODE Basic
ENST00000971094.2MAP4K4-25174661087aaENSP00000641153.1
 
Protein coding
--GENCODE PrimaryGENCODE Basic
ENST00000971085.2MAP4K4-24274541083aaENSP00000641144.1
 
Protein coding
--GENCODE Basic
ENST00000971093.2MAP4K4-25072921029aaENSP00000641152.1
 
Protein coding
--GENCODE PrimaryGENCODE Basic
ENST00000933918.1MAP4K4-23170481155aaENSP00000603977.1
 
Protein coding
--GENCODE Basic
ENST00000417294.5MAP4K4-20542511170aaENSP00000409720.1
 
Protein coding
H7C360 -TSL:5CDS 5' incomplete
ENST00000456652.5MAP4K4-21038551038aaENSP00000387370.1
 
Protein coding
E7EX83 -GENCODE BasicTSL:5
ENST00000347699.8MAP4K4-20237921239aaENSP00000314363.6
 
Protein coding
CCDS56130O95819-1 -GENCODE BasicAPPRIS ALT1TSL:1
ENST00000421882.5MAP4K4-20734161056aaENSP00000396066.1
 
Protein coding
H7C0P6 -TSL:5CDS 5' incomplete
ENST00001107335.1MAP4K4-2532854440aaENSP00000777140.1
 
Protein coding
--GENCODE PrimaryGENCODE Basic
ENST00000418101.1MAP4K4-206776258aaENSP00000414766.1
 
Protein coding
H7C3Z6 -TSL:3CDS 5' and 3' incomplete
ENST00000427603.5MAP4K4-209526102aaENSP00000403016.1
 
Protein coding
E7ETN6 -TSL:4CDS 3' incomplete
ENST00001113756.1MAP4K4-2542625239aaENSP00000783561.1
 
Nonsense mediated decay
---
ENST00000627726.3MAP4K4-2174232No protein-
 
Protein coding CDS not defined
--TSL:5
ENST00000498066.1MAP4K4-2151017No protein-
 
Protein coding CDS not defined
--TSL:2
ENST00000476609.1MAP4K4-2113598No protein-
 
Retained intron
--TSL:2
ENST00000491743.1MAP4K4-214646No protein-
 
Retained intron
--TSL:4
ENST00000477711.1MAP4K4-212606No protein-
 
Retained intron
--TSL:2
ENST00000489490.1MAP4K4-213362No protein-
 
Retained intron
--TSL:3