Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Biological process
- GO: Molecular function
- GO: Cellular component
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
External references
Supporting evidence
ID History
- Gene history

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Gene: IDE ENSBTAG00000019759

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Description

insulin degrading enzyme [Source:VGNC Symbol;Acc:VGNC:30033]

Location

Primary_assembly 26: 13,883,715-13,976,371 reverse strand.

ARS-UCD2.0:CM008193.2

About this gene

This gene has 5 transcripts (splice variants), 224 orthologues and 8 paralogues.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSBTAT00000100692.1	IDE-204	3375	1019aa	ENSBTAP00000102566.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0AAA9U0H2	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,
ENSBTAT00000112218.1	IDE-201	3327	1003aa	ENSBTAP00000083212.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0AAA9SHK7	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSBTAT00000026332.6	IDE-205	3014	998aa	ENSBTAP00000026332.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0AAF6Z6W2	-
ENSBTAT00000112234.1	IDE-202	2920	928aa	ENSBTAP00000092073.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0AAA9T682	-
ENSBTAT00000114163.1	IDE-203	2752	872aa	ENSBTAP00000099597.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0AAA9TSW7	-

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Summary

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