Gene: NPC1 ENSBTAG00000015195

Description

NPC intracellular cholesterol transporter 1 [Source:VGNC Symbol;Acc:VGNC:32194]

Location

ARS-UCD2.0:CM008191.2

About this gene

This gene has 2 transcripts (splice variants), 209 orthologues, 10 paralogues and is associated with 1 phenotype.

Transcripts

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSBTAT00000068752.3	NPC1-201	5024	1291aa	ENSBTAP00000069520.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A3Q1NDF8	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSBTAT00000020219.7	NPC1-202	5064	1254aa	ENSBTAP00000020219.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0AAF6DMC2	APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,

Summary