DNA topoisomerase II binding protein 1 [Source:VGNC Symbol;Acc:VGNC:49585]
Primary_assembly 1: 135,753,573-135,824,765 forward strand.
ARS-UCD1.3:CM008168.2
This gene has 4 transcripts (splice variants), 199 orthologues and 1 paralogue.
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
|---|---|---|---|---|---|---|---|
| ENSBTAT00000084226.2 | TOPBP1-201 | 5193 | 1546aa | ENSBTAP00000067344.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A0A3Q1MST6 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, |
| ENSBTAT00000000686.7 | TOPBP1-204 | 5341 | 1528aa | ENSBTAP00000000686.7 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | G3X684 | APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2, |
| ENSBTAT00000078321.2 | TOPBP1-203 | 5194 | 1533aa | ENSBTAP00000059732.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A0A3Q1LWE4 | APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2, |
| ENSBTAT00000078550.2 | TOPBP1-202 | 4944 | 1463aa | ENSBTAP00000058449.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | A0A3Q1LNB2 | APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2, |
