Autophagy-related protein and dual specificity member of the E1 family; mediates the attachment of Atg12p to Atg5p and Atg8p to phosphatidylethanolamine which are required steps in autophagosome formation; E1 enzymes are also known as ubiquitin-activating enzymes; involved in methionine restriction extension of chronological lifespan in an autophagy-dependent manner [Source:SGD;Acc:S000001214]

APG11, APG7, CVT2

Chromosome VIII: 445,713-447,605 forward strand.

This transcript has 1 exon, is annotated with 12 domains and features, is associated with 42 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YHR171W Show transcript tableHide transcript table