High-mobility group (HMG) protein; binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to chromosomes; functionally redundant with Nhp6Bp; required for transcriptional initiation fidelity of some tRNA genes; homologous to mammalian HMGB1 and HMGB2; NHP6A has a paralog, NHP6B, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000006256]
Chromosome XVI: 665,693-665,974 reverse strand.
R64-1-1:BK006949.2
This gene has 1 transcript (splice variant) and 1 paralogue.
Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
---|---|---|---|---|---|---|---|
YPR052C_mRNA | NHP6A | 282 | 93aa | YPR052C | Protein coding | P11632 | Ensembl Canonical, |