Description
Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]
Gene Synonyms
PAC15
Location
Chromosome XVI: 156,490-157,593 reverse strand.
R64-1-1:BK006949.2
About this gene
This gene has 1 transcript (splice variant).
Transcripts
