Description
mRNA cap binding protein and translation initiation factor eIF4E; the eIF4E-cap complex is responsible for mediating cap-dependent mRNA translation via interactions with translation initiation factor eIF4G (Tif4631p or Tif4632p); protein abundance increases in response to DNA replication stress; mutants are defective for adhesion and pseudohyphal growth; human homolog EIF4E can complement yeast cdc33 null mutant [Source:SGD;Acc:S000005499]
Gene Synonyms
TIF45, eIF4E
Location
Chromosome XV: 60,383-61,024 reverse strand.
R64-1-1:BK006948.2
About this gene
This gene has 1 transcript (splice variant) and 1147 orthologues.
Transcripts
