MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]
Chromosome XIV: 680,694-685,433 reverse strand.
R64-1-1:BK006947.3
This gene has 1 transcript (splice variant) and 8 paralogues.
Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
---|---|---|---|---|---|---|---|
YNR031C_mRNA | SSK2 | 4740 | 1579aa | YNR031C | Protein coding | P53599 | Ensembl Canonical, |