Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication [Source:SGD;Acc:S000005251]
CMS1, YPK1
Chromosome XIV: 56,446-57,573 reverse strand.
R64-1-1:BK006947.3
This gene has 1 transcript (splice variant), 2 orthologues and 2 paralogues.
Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
---|---|---|---|---|---|---|---|
YNL307C_mRNA | MCK1 | 1128 | 375aa | YNL307C | Protein coding | P21965 | Ensembl Canonical, |