Description
Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis; with Sdo1p, a guanine nucleotide exchange factor (GEF), promotes release of Tif6p from 60S ribosomal subunits in the cytoplasm so that they can assemble with 40S subunits to generate mature ribosomes; required for quality control check of newly made large ribosomal subunits before they are released into the pool of translating ribosomes [Source:SGD;Acc:S000005107]
Gene Synonyms
EFL1
Location
Chromosome XIV: 326,741-330,073 reverse strand.
R64-1-1:BK006947.3
About this gene
This gene has 1 transcript (splice variant), 227 orthologues and 15 paralogues.
Transcripts
