Description
GMP synthase; highly conserved enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation; reduction-of-function mutation gua1-G388D causes changes in cellular guanine nucleotide pools, defects in general protein synthesis, and impaired translation of GCN4 mRNA [Source:SGD;Acc:S000004830]
Location
Chromosome XIII: 701,790-703,367 forward strand.
R64-1-1:BK006946.2
About this gene
This gene has 1 transcript (splice variant) and 216 orthologues.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
|---|---|---|---|---|---|---|---|
| YMR217W_mRNA | GUA1 | 1578 | 525aa | YMR217W | Protein coding | P38625 | Ensembl Canonical, |
