Scaffold-type E3 ligase; required for cullin neddylation and ubiquitin ligase activation; contains a ubiquitin-binding domain (UBA) for ubiquitin and Nedd8 (Rub1p) interaction and a PONY domain involved in cullin binding and neddylation [Source:SGD;Acc:S000004118]

Chromosome XII: 398,530-399,433 forward strand.

R64-1-1:BK006945.2

This gene has 1 transcript (splice variant) and 228 orthologues.

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