Description
Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]
Gene Synonyms
SSK3
Location
Chromosome XII: 371,620-372,927 forward strand.
R64-1-1:BK006945.2
About this gene
This gene has 1 transcript (splice variant), 464 orthologues and 3 paralogues.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
|---|---|---|---|---|---|---|---|
| YLR113W_mRNA | HOG1 | 1308 | 435aa | YLR113W | Protein coding | P32485 | Ensembl Canonical, |
