Protein required for maturation of mitochondrial [4Fe-4S] proteins; functions in a complex with Isa2p and possibly Iba57p; isa1 deletion causes loss of mitochondrial DNA and respiratory deficiency; depletion reduces growth on nonfermentable carbon sources; functional ortholog of bacterial A-type ISC proteins; human ISCA1 can complement isa1 null mutant [Source:SGD;Acc:S000003950]
Chromosome XII: 87,403-88,155 forward strand.
R64-1-1:BK006945.2
This gene has 1 transcript (splice variant), 271 orthologues and 1 paralogue.