Description
Translation initiation factor eIF4A; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G; protein abundance increases in response to DNA replication stress; TIF1 has a paralog, TIF2, that arose from the whole genome duplication [Source:SGD;Acc:S000001767]
Gene Synonyms
eIF4A
Location
Chromosome XI: 554,987-556,174 forward strand.
R64-1-1:BK006944.2
About this gene
This gene has 1 transcript (splice variant), 233 orthologues and 22 paralogues.
Transcripts
