Description
Protein kinase; along with its paralog, ALK2, required for proper spindle positioning and nuclear segregation following mitotic arrest, proper organization of cell polarity factors in mitosis, proper localization of formins and polarity factors, and survival in cells that activate spindle assembly checkpoint; phosphorylated in response to DNA damage; ALK1 has a paralog, ALK2, that arose from the whole genome duplication; similar to mammalian haspins [Source:SGD;Acc:S000002989]
Location
Chromosome VII: 454,785-457,067 forward strand.
R64-1-1:BK006941.2
About this gene
This gene has 1 transcript (splice variant), 629 orthologues and 1 paralogue.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
|---|---|---|---|---|---|---|---|
| YGL021W_mRNA | ALK1 | 2283 | 760aa | YGL021W | Protein coding | P43633 | Ensembl Canonical, |
