C-3 sterol dehydrogenase; catalyzes the second of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; human homolog NSDHL implicated in CK syndrome, and can complement yeast null mutant; molecular target of natural product and antifungal compound FR171456 [Source:SGD;Acc:S000002969]
Chromosome VII: 495,453-496,502 reverse strand.
R64-1-1:BK006941.2
This gene has 1 transcript (splice variant), 215 orthologues and 5 paralogues.