Description
Cytoplasmic thioredoxin reductase; key regulatory enzyme that determines the redox state of the thioredoxin system, which acts as a disulfide reductase system and protects cells against both oxidative and reductive stress; protein abundance increases in response to DNA replication stress; TRR1 has a paralog, TRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000002761]
Location
Chromosome IV: 1,183,299-1,184,258 forward strand.
R64-1-1:BK006938.2
About this gene
This gene has 1 transcript (splice variant), 1333 orthologues and 4 paralogues.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
|---|---|---|---|---|---|---|---|
| YDR353W_mRNA | TRR1 | 960 | 319aa | YDR353W | Protein coding | P29509 | Ensembl Canonical, |
