Homocitrate synthase isozyme; catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; LYS21 has a paralog, LYS20, that arose from the whole genome duplication [Source:SGD;Acc:S000002289]
Chromosome IV: 227,393-228,715 forward strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant), 401 orthologues and 3 paralogues.
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
|---|---|---|---|---|---|---|---|
| YDL131W_mRNA | LYS21 | 1323 | 440aa | YDL131W | Protein coding | Q12122 | Ensembl Canonical, |

