Description
Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]
Gene Synonyms
RPK1
Location
Chromosome IV: 400,997-403,291 reverse strand.
R64-1-1:BK006938.2
About this gene
This gene has 1 transcript (splice variant) and 760 orthologues.
Transcripts
