Glutathione-dependent disulfide oxidoreductase; hydroperoxide and superoxide-radical responsive, heat-stable, with active site cysteine pair; protects cells from oxidative damage; GRX1 has a paralog, GRX2, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000000540]
Chromosome III: 60,841-61,173 reverse strand.
R64-1-1:BK006937.2
This gene has 1 transcript (splice variant), 188 orthologues and 3 paralogues.