Description
Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]
Gene Synonyms
CDK1, HSL5, SRM5
Location
Chromosome II: 560,078-560,974 forward strand.
R64-1-1:BK006936.2
About this gene
This gene has 1 transcript (splice variant), 391 orthologues and 6 paralogues.
Transcripts
