Description
G1 cyclin involved in cell cycle progression; activates Cdc28p kinase to promote G1 to S phase transition; plays a role in regulating transcription of other G1 cyclins, CLN1 and CLN2; regulated by phosphorylation and proteolysis; acetyl-CoA induces CLN3 transcription in response to nutrient repletion to promote cell-cycle entry; cell cycle arrest phenotype of the cln1 cln2 cln3 triple null mutant is complemented by any of human cyclins CCNA2, CCNB1, CCNC, CCND1, or CCNE1 [Source:SGD;Acc:S000000038]
Gene Synonyms
DAF1, FUN10, WHI1
Location
Chromosome I: 65,778-67,520 reverse strand.
R64-1-1:BK006935.2
About this gene
This gene has 1 transcript (splice variant).
Transcripts
