Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
- GO: Anatomical entity
Phenotypes
Genetic Variation
- Variant table
- Variant image
- Structural variants
Gene expression
Pathway
Molecular interactions
External references
Supporting evidence
ID History
- Gene history

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Gene: Top1 ENSRNOG00000047611

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Description

DNA topoisomerase I [Source:RGD Symbol;Acc:621246]

Gene Synonyms

Ab2-086

Location

Primary_assembly 3: 169,713,130-169,796,327 forward strand.

GRCr8:CM070393.1

About this gene

This gene has 1 transcript (splice variant), 273 orthologues, 1 paralogue and is associated with 8 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSRNOT00000113376.2	Top1-201	3768	767aa	ENSRNOP00000076575.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8I5Y067 A6JWZ1 Q9WUL0	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1,

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Paralogues

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